Basic scientific and animal research is helping us discern the underlying brain mechanisms that cause or increase the risk of developing cerebral palsy, investigate novel treatment strategies, and gain a better understanding of how and why current therapies work.
Using established rodent models of hemiplegic CP; researchers have been able to study how to improve CIMT with stem cell based regenerative approaches. Researchers are uncovering the mechanisms of how inflammation in the brain is related to CP using mice.
Children with Cerebral Palsy (CP) who were born premature face a lifetime of motor impairments, some of which can be treated with physiotherapy. Recent findings suggest that the drug metformin could help motor recovery by recruiting stem cells in the brain to help repair injury. Here, we will evaluate whether metformin combined with physiotherapy enhances motor and thinking skills in children with cerebral palsy.